Not Just the Stomach Flu: A Case of Acute Liver Failure after Adenovirus Infection

Adenovirus is a common viral infection with variable clinical presentations, including respiratory tract infection, conjunctivitis, and gastroenteritis. In immunocompromised patients, it can present more severely with liver failure, renal failure, encephalitis, pancreatitis, myocarditis, and even disseminated disease. We report a case of acute liver failure caused by adenovirus in a previously healthy two-year-old child, whose illness spontaneously resolved. Although adenovirus is a rare cause of fulminant liver failure, it should be considered in the differential diagnosis, even in presumably immunocompetent children.